ABSTRACT
Introduction: Iron deficiency anemia (IDA) is the mostcommon nutritional deficiency worldwide. It can causereduced work capacity in adults and impact motor and mentaldevelopment in children and adolescents. Aim of the currentresearch was to study the lymphocytic count in premenopausalwomen with iron deficiency anemia.Material and methods: The study was conducted in theDepartment of General Pathology of the medical institution.For the study, we selected 100 pre-menopausal womenbetween the age group of 18-40 years who were diagnosedwith iron deficiency anemia and their hemoglobin level wasless than 10 g/dL. 100 pre-menopausal women with normalhemoglobin level were recruited after matching with thesubjects for control group. The patients with thalassemia,leukemia or any other chronic and autoimmune disease wereexcluded from the study. Laboratory evaluation of eachsubject was done.Results: The mean age of the patients in study group was 32.67years and in control group was 34.58 years. There were 100subjects in each group. Table 2 shows the mean lymphocytecount in peripheral venous blood in pre-menopausal womenwith Iron deficiency anemia and normal healthy women. Themean CD3+, CD4+, CD8+, and CD19+ lymphocyte countswere 1.66, 0.71, 0.66, 0.41, 1.18 X 109/L, respectively, instudy group, and 1.82, 0.59, 0.81, 0.31 and 1.59 X 109/L,respectively, for the control group.Conclusion: Within the limitations of the study, this can beconcluded that significant change in seen in the lymphocytecount in premenopausal women with iron deficiency anemia.
ABSTRACT
Background: Hepatitis C virus exhibits a varied geneticdiversity that shows regional variations in the genotypicprevalence. Hepatitis C virus is a globally prevalent pathogenthat is a major cause of death and morbidity. The most recentstudies determining the disease burden showed an elevation insero prevalence over the last 15 years to 2.8%, similiar to >185million infections around the world. The present study wasconducted with the aim to determine different Genotypicvariation of Hepatitis C Amongst Subjects Reporting to thehospital.Materials and Methods: The present study included 438subjects with hepatitis that reported to the reporting to theDepartment of General Pathology, Career Institute of MedicalSciences and Hospital, Ghailla, Lucknow, Uttar Pradesh, India.The serum obtained was mixed with guanidinium thiocyanate,betamercaptoethanol and sarcosyl. Phenol and chloroformwere used for extracting RNA followed by precipitation withisopropanol. The genotypes thus obtained were made to matchwith the chart obtained by the manufacturer. All the resultsobtained were arranged in the tabulated form and analysedusing SPSS software.Results: There were 73 males and 34 females with genotype1. There was 1 male with genotype 2. There were 72 malesand 55 females with genotype 3. There were 38 males and 20females with genotype 4. There were 26 males and 12females with genotype 1. There were 49 males and 29 femaleswith genotype 3.Conclusion: From the above study it can be concludedthat genotype 3 is most prevalent amongst subjects withhepatitis C.